The field of structure based drug design is a rapidly growing area in which many successes have occurred in recent years the explosion of genomic proteomic and structural information has provided hundreds of new targets and opportunities for future drug lead discovery. In order to rapidly discover lead compounds for clinical use we initiated a program of combined structure assisted drug design virtual drug screening and high throughput screening to identify new drug leads that target the covid 19 main protease mpro. Structure based drug design structure based drug design is the process of designing a chemical structure with the objective of identifying a compound which suits for clinical tests the process involves how that shapes and charges to interact with biological target inorder to yield therapeutic activity. Introduction to structure based drug design a practical guide tara phillips drug discovery to drug development pipeline o preexisting target o literature target o genomics o proteomics identification o hts o de novo design o virtual screening optimization
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